6rrc

X-ray diffraction
2.37Å resolution

Crystal structure of the N-terminal region of human cohesin subunit STAG1 in complex with RAD21 peptide

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cohesin subunit SA-1 Chains: A, C
Molecule details ›
Chains: A, C
Length: 339 amino acids
Theoretical weight: 39.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WVM7 (Residues: 86-420; Coverage: 27%)
Gene names: SA1, SCC3, STAG1
Sequence domains: STAG domain
64-kDa C-terminal product Chains: B, D
Molecule details ›
Chains: B, D
Length: 25 amino acids
Theoretical weight: 2.9 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O60216 (Residues: 321-345; Coverage: 4%)
Gene names: HR21, KIAA0078, NXP1, RAD21, SCC1

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: C222
Unit cell:
a: 117.077Å b: 151.662Å c: 126.656Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.214 0.248
Expression systems:
  • Escherichia coli
  • Not provided