6rqx

X-ray diffraction
1.68Å resolution

High-resolution crystal structure of ERAP1 in complex with 10mer phosphinic peptide

Released:
Source organism: Homo sapiens
Entry authors: Giastas P, Stratikos E

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Endoplasmic reticulum aminopeptidase 1 Chain: A
Molecule details ›
Chain: A
Length: 938 amino acids
Theoretical weight: 106.94 KDa
Source organism: Homo sapiens
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: Q9NZ08 (Residues: 1-938; Coverage: 100%)
Gene names: APPILS, ARTS1, ERAP1, KIAA0525, UNQ584/PRO1154
Sequence domains:
PSE-LYS-HIS-HIS-ALA-PHE-SER-PHE-LYS Chain: B
Molecule details ›
Chain: B
Length: 9 amino acids
Theoretical weight: 1.3 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P13 (MX1)
Unit cell:
a: 58.004Å b: 116.439Å c: 147.363Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.176 0.176 0.209
Expression systems:
  • Spodoptera aff. frugiperda 1 BOLD-2017
  • Not provided