6rlt

X-ray diffraction
1.84Å resolution

Trypanosoma brucei Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-Sulfamoyl)uridine

Released:

Function and Biology Details

Reaction catalysed:
ATP + L-serine + tRNA(Sec) = AMP + diphosphate + L-seryl-tRNA(Sec)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
AA_TRNA_LIGASE_II domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 479 amino acids
Theoretical weight: 53.92 KDa
Source organism: Trypanosoma brucei gambiense
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: D0A7P1 (Residues: 1-479; Coverage: 100%)
Gene name: TbgDal_XI8110
Sequence domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: R32
Unit cell:
a: 177.609Å b: 177.609Å c: 246.109Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.213 0.213 0.239
Expression system: Escherichia coli BL21(DE3)