6rga

X-ray diffraction
2.18Å resolution

Crystal structure of NAD kinase 1 from Listeria monocytogenes in complexe with an inhibitor

Released:
Source organism: Listeria monocytogenes EGD-e
Entry authors: Gelin M, Labesse G

Function and Biology Details

Reaction catalysed:
ATP + NAD(+) = ADP + NADP(+)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NAD kinase 1 Chain: A
Molecule details ›
Chain: A
Length: 272 amino acids
Theoretical weight: 31.05 KDa
Source organism: Listeria monocytogenes EGD-e
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8Y8D7 (Residues: 1-264; Coverage: 100%)
Gene names: lmo0968, nadK1
Sequence domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: I222
Unit cell:
a: 63.18Å b: 74.73Å c: 118.73Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.213 0.238
Expression system: Escherichia coli