6rft

X-ray diffraction
2.3Å resolution

Crystal structure of Eis2 from Mycobacterium abscessus bound to Acetyl-CoA

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Uncharacterized N-acetyltransferase SAMEA2071181_03011 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 411 amino acids
Theoretical weight: 45.5 KDa
Source organism: Mycobacteroides abscessus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A1M9A4M7 (Residues: 2-411; Coverage: 100%)
Gene names: SAMEA2071181_03011, SAMEA2259684_02562, SAMEA2275847_00725, eis, eis_1, eis_2
Sequence domains:

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P21
Unit cell:
a: 111.65Å b: 76.99Å c: 152.56Å
α: 90° β: 90.81° γ: 90°
R-values:
R R work R free
0.23 0.229 0.267
Expression system: Escherichia coli BL21(DE3)