6raj

Electron Microscopy
3.5Å resolution

Heterodimeric ABC exporter TmrAB in vanadate trapped outward-facing open conformation

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-212440 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Multidrug resistance ABC transporter ATP-binding and permease protein Chain: A
Molecule details ›
Chain: A
Length: 623 amino acids
Theoretical weight: 70.66 KDa
Source organism: Thermus thermophilus HB27
Expression system: Escherichia coli
UniProt:
  • Canonical: Q72J05 (Residues: 1-600; Coverage: 100%)
Gene name: TT_C0976
Sequence domains:
Multidrug resistance ABC transporter ATP-binding and permease protein Chain: B
Molecule details ›
Chain: B
Length: 578 amino acids
Theoretical weight: 64.63 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q72J04 (Residues: 1-578; Coverage: 100%)
Gene name: TT_C0977
Sequence domains:
Nanobody Nb9F10 Chain: C
Molecule details ›
Chain: C
Length: 136 amino acids
Theoretical weight: 14.59 KDa
Source organism: Vicugna pacos
Expression system: Escherichia coli

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-4777
Expression system: Escherichia coli