6r15

X-ray diffraction
1.82Å resolution

Crystal structure of the SUN1-KASH1 6:6 complex

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
PDBe Complex ID:
PDB-CPX-131791 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
SUN domain-containing protein 1 Chain: A
Molecule details ›
Chain: A
Length: 203 amino acids
Theoretical weight: 22.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O94901 (Residues: 589-785; Coverage: 25%)
Gene names: KIAA0810, SUN1, UNC84A
Sequence domains: Sad1 / UNC-like C-terminal
Nesprin-1 Chain: B
Molecule details ›
Chain: B
Length: 32 amino acids
Theoretical weight: 3.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8NF91 (Residues: 8769-8797; Coverage: 0%)
Gene names: C6orf98, KIAA0796, KIAA1262, KIAA1756, MYNE1, SYNE1
Sequence domains: Nuclear envelope localisation domain

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P6322
Unit cell:
a: 80.45Å b: 80.45Å c: 182.55Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.16 0.159 0.182
Expression system: Escherichia coli