Solution NMR

Solution structure of the free FOXO1 DNA binding domain


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Forkhead box protein O1 Chain: A
Molecule details ›
Chain: A
Length: 119 amino acids
Theoretical weight: 13.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q12778 (Residues: 159-272; Coverage: 17%)
Gene names: FKHR, FOXO1, FOXO1A
Sequence domains: Forkhead domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 89%
Refinement method: molecular dynamics
Expression system: Escherichia coli BL21(DE3)