Structure analysis

NgCKK (N.Gruberi CKK) decorated 13pf taxol-GDP microtubule

Electron Microscopy
3.8Å resolution
Source organisms:
Assembly composition:
hetero pentamer (preferred)
Entry contents: 3 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero pentamer
Accessible surface area: 67200 Å2
Buried surface area: 18500 Å2
Dissociation area: 2,100 Å2
Dissociation energy (ΔGdiss): -14 kcal/mol
Dissociation entropy (TΔSdiss): 28 kcal/mol
Interface energy (ΔGint): -95 kcal/mol
Symmetry number: 1

Macromolecules

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Chain: W
Length: 187 amino acids
Theoretical weight: 20.88 KDa
Source organism: Naegleria gruberi
Expression system: Escherichia coli
UniProt:
  • Canonical: D2VJG4 (Residues: 621-788; Coverage: 21%)
Gene name: NAEGRDRAFT_50049
Pfam: Microtubule-binding calmodulin-regulated spectrin-associated
InterPro:

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