Function and Biology Details
Reaction catalysed:
ATP-dependent breakage, passage and rejoining of double-stranded DNA
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- DNA topoisomerase, type IIA, domain A
- TOPRIM domain
- DNA topoisomerase, type IIA-like domain superfamily
- DNA gyrase B subunit, C-terminal
- DNA topoisomerase, type IIA, conserved site
- DNA gyrase subunit B, TOPRIM domain
- DNA topoisomerase, type IIA, subunit B, C-terminal
- DNA topoisomerase, type IIA
2 more domains
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
DNA gyrase and DNA (preferred)
PDBe Complex ID:
PDB-CPX-120504 (preferred)
Entry contents:
2 distinct polypeptide molecules
1 distinct DNA molecule
1 distinct DNA molecule
Macromolecules (3 distinct):
DNA gyrase subunit B
Molecule details ›
Chains: B, D
Length: 202 amino acids
Theoretical weight: 22.61 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 202 amino acids
Theoretical weight: 22.61 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
- Canonical:
P66937 (Residues: 409-543, 580-644; Coverage: 31%)
Sequence domains:
DNA gyrase subunit A
Molecule details ›
Chains: A, C
Length: 490 amino acids
Theoretical weight: 55.54 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
Sequence domains: DNA gyrase/topoisomerase IV, subunit A
Length: 490 amino acids
Theoretical weight: 55.54 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
- Canonical: Q99XG5 (Residues: 2-491; Coverage: 55%)
Sequence domains: DNA gyrase/topoisomerase IV, subunit A
