6qpf

X-ray diffraction
3.63Å resolution

Influenza A virus Polymerase Heterotrimer A/duck/Fujian/01/2002(H5N1)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Polymerase acidic protein Chains: A, D, G, J
Molecule details ›
Chains: A, D, G, J
Length: 716 amino acids
Theoretical weight: 82.71 KDa
Source organism: Influenza A virus (A/duck/Fujian/01/2002(H5N1))
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: D3YNB8 (Residues: 1-716; Coverage: 100%)
Gene name: PA
Sequence domains: Influenza RNA-dependent RNA polymerase subunit PA
RNA-directed RNA polymerase catalytic subunit Chains: B, E, H, K
Molecule details ›
Chains: B, E, H, K
Length: 757 amino acids
Theoretical weight: 86.55 KDa
Source organism: Influenza A virus (A/duck/Fujian/01/2002(H5N1))
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: D3YNB6 (Residues: 1-757; Coverage: 100%)
Gene name: PB1
Sequence domains: Influenza RNA-dependent RNA polymerase subunit PB1
Polymerase basic protein 2 Chains: C, F, I, L
Molecule details ›
Chains: C, F, I, L
Length: 765 amino acids
Theoretical weight: 86.82 KDa
Source organism: Influenza A virus (A/duck/Fujian/01/2002(H5N1))
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: D3YNB5 (Residues: 1-759; Coverage: 100%)
Gene name: PB2
Sequence domains: Influenza RNA-dependent RNA polymerase subunit PB2

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: C2
Unit cell:
a: 337.122Å b: 192.859Å c: 235.688Å
α: 90° β: 91.46° γ: 90°
R-values:
R R work R free
0.279 0.277 0.323
Expression system: Spodoptera frugiperda