› 6q44

Solution NMR

Est3 telomerase subunit in the yeast Hansenula polymorpha

Released:
DOI: 10.2210/pdb6q44/pdb
PDB entry 6q44 coloured by chain, ensemble of 20 models, front view.
PDB entry 6q44 coloured by chain, ensemble of 20 models, side view.
PDB entry 6q44 coloured by chain, ensemble of 20 models, top view.
Source organism: Ogataea parapolymorpha DL-1
Primary publication:
Insights into the structure and function of Est3 from the Hansenula polymorpha telomerase.
Shepelev NM, Mariasina SS, Mantsyzov AB, Malyavko AN, Efimov SV, Petrova OA, Rodina EV, Zvereva MI, Dontsova OA, Polshakov VI
Sci Rep 10 11109 (2020)
PMID: 32632130

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-197724 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Telomere replication protein EST3 Chain: A
Molecule details ›
Chain: A
Length: 178 amino acids
Theoretical weight: 20.48 KDa
Source organism: Ogataea parapolymorpha DL-1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: W1QJK4 (Residues: 2-175; Coverage: 99%)
Gene name: HPODL_02192
Sequence domains: Shelterin complex subunit, TPP1/ACD

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 80%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Post-Transcriptional and Post-Translational Modifications in Telomerase Biogenesis and Recruitment to Telomeres.
Shepelev et al. (2023)
1 more

1 mention without citation

Insights into the structure and function of Est3 from the Hansenula polymorpha telomerase.
Shepelev et al. (2020)