6q38

X-ray diffraction
1.74Å resolution

The Crystal structure of CK2a bound to P1-C4

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Casein kinase II subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 327 amino acids
Theoretical weight: 39.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P68400 (Residues: 3-329; Coverage: 84%)
  • Best match: P68400-2 (Residues: 1-193)
Gene names: CK2A1, CSNK2A1
Sequence domains: Protein kinase domain
Casein kinase II subunit beta Chain: C
Molecule details ›
Chain: C
Length: 9 amino acids
Theoretical weight: 1.64 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P67870 (Residues: 186-193; Coverage: 4%)
Gene names: CK2N, CSNK2B, G5A

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P21212
Unit cell:
a: 60.887Å b: 127.752Å c: 54.499Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.204 0.234
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided