6pt2

X-ray diffraction
2.8Å resolution

Crystal structure of the active delta opioid receptor in complex with the peptide agonist KGCHM07

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Delta opioid receptor Chains: A, B
Molecule details ›
Chains: A, B
Length: 454 amino acids
Theoretical weight: 51.06 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
Peptide agonist KGCHM07 Chains: C, D
Molecule details ›
Chains: C, D
Length: 5 amino acids
Theoretical weight: 824 Da
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

3 bound ligands:

3 modified residues:

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P212121
Unit cell:
a: 48.96Å b: 140.88Å c: 158.64Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.247 0.246 0.282
Expression systems:
  • Spodoptera frugiperda
  • Not provided