› › Structure analysis

WDR5delta32 bound to N-(4-(4-(hydroxymethyl)-1H-imidazol-2-yl)butyl)acrylamide

X-ray diffraction
1.54Å resolution
PDB entry 6pgf coloured by chain, front view.
PDB entry 6pgf coloured by chain, side view.
PDB entry 6pgf coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: WD repeat-containing protein 5
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Multimeric state: monomeric
Accessible surface area: 11947.29 Å2
Buried surface area: 499.42 Å2
Dissociation area: 67.86 Å2
Dissociation energy (ΔGdiss): 9.18 kcal/mol
Dissociation entropy (TΔSdiss): 0.57 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-158474

Macromolecules

WD repeat-containing protein 5
Chain: A
Length: 305 amino acids
Theoretical weight: 33.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P61964 (Residues: 32-334; Coverage: 91%)
Gene names: BIG3, WDR5
Pfam: WD domain, G-beta repeat
InterPro:
WD repeat-containing protein 5 in PDB entry 6pgf, assembly 1, front view.
WD repeat-containing protein 5 in PDB entry 6pgf, assembly 1, side view.
WD repeat-containing protein 5 in PDB entry 6pgf, assembly 1, top view.
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