› 6pce

X-ray diffraction
1.65Å resolution

Human Coa6

Released:
DOI: 10.2210/pdb6pce/pdb
PDB entry 6pce coloured by chain, front view.
PDB entry 6pce coloured by chain, side view.
PDB entry 6pce coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural and functional characterization of the mitochondrial complex IV assembly factor Coa6.
Maghool S, Cooray NDG, Stroud DA, Aragão D, Ryan MT, Maher MJ
Life Sci Alliance 2 (2019)
PMID: 31515291

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177337 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytochrome c oxidase assembly factor 6 homolog Chains: A, B
Molecule details ›
Chains: A, B
Length: 70 amino acids
Theoretical weight: 8.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5JTJ3 (Residues: 50-119; Coverage: 56%)
Gene names: C1orf31, COA6
Sequence domains: Cytochrome oxidase c subunit VIb

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P212121
Unit cell:
a: 31.95Å b: 52.409Å c: 78.296Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.192 0.188 0.229
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Regulation of COX Assembly and Function by Twin CX9C Proteins-Implications for Human Disease.
Gladyck et al. (2021)
2 more

2 mentions without citation

What Role Does COA6 Play in Cytochrome C Oxidase Biogenesis: A Metallochaperone or Thiol Oxidoreductase, or Both?
Maghool et al. (2020)
1 more