X-ray diffraction
1.9Å resolution

Function and Biology Details

Reaction catalysed:
(3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-3-O-((3R)-hydroxytetradecanoyl)-alpha-D-glucosamine = UDP-2-N,3-O-bis((3R)-3-hydroxytetradecanoyl)-alpha-D-glucosamine + a holo-[acyl-carrier-protein]
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 343 amino acids
Theoretical weight: 36.1 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P21645 (Residues: 3-341; Coverage: 99%)
Gene names: JW0174, b0179, firA, lpxD, omsA
Sequence domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P3221
Unit cell:
a: 97.213Å b: 97.213Å c: 216.185Å
α: 90° β: 90° γ: 120°
R R work R free
0.181 0.18 0.207
Expression system: Escherichia coli BL21(DE3)