› 6out

Electron Microscopy
2.6Å resolution

Asymmetric focused reconstruction of human norovirus GI.1 Norwalk strain VLP asymmetric unit in T=3 symmetry

Released:
DOI: 10.2210/pdb6out/pdb
PDB entry 6out coloured by chain, front view.
PDB entry 6out coloured by chain, side view.
PDB entry 6out coloured by chain, top view.
Source organism: Norovirus Hu/1968/US
Primary publication:
High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Jung J, Grant T, Thomas DR, Diehnelt CW, Grigorieff N, Joshua-Tor L
Proc Natl Acad Sci U S A 116 12828-12832 (2019)
PMID: 31182604
Related structures: EMD-20205

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182867 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein VP1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 530 amino acids
Theoretical weight: 56.63 KDa
Source organism: Norovirus Hu/1968/US
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q83884 (Residues: 1-530; Coverage: 100%)
Gene name: ORF2
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.6Å
Relevant EMDB volumes: EMD-20205
Expression system: Spodoptera frugiperda

Quick links

Citations

5 review citations

Applications of Charge Detection Mass Spectrometry in Molecular Biology and Biotechnology.
Jarrold MF. (2022)
4 more

2 mentions without citation

High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Jung et al. (2019)
1 more