X-ray diffraction
1.8Å resolution

Crystal Structure of the D478S Variant of the Myocilin Olfactomedin Domain


Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Myocilin, C-terminal fragment Chain: A
Molecule details ›
Chain: A
Length: 277 amino acids
Theoretical weight: 31.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q99972 (Residues: 228-504; Coverage: 59%)
Gene names: GLC1A, MYOC, TIGR
Sequence domains: Olfactomedin-like domain

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P212121
Unit cell:
a: 45.353Å b: 57.241Å c: 90.474Å
α: 90° β: 90° γ: 90°
R R work R free
0.152 0.15 0.173
Expression system: Escherichia coli