6orq

Electron Microscopy
4.4Å resolution

Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab275MUR

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
PDBe Complex ID:
PDB-CPX-212155 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (7 distinct):
Transmembrane protein gp41 Chains: A, C, F
Molecule details ›
Chains: A, C, F
Length: 148 amino acids
Theoretical weight: 16.74 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 514-661; Coverage: 17%)
Gene name: env
Sequence domains: Retroviral envelope protein
Envelope glycoprotein gp160 Chains: B, G, I
Molecule details ›
Chains: B, G, I
Length: 473 amino acids
Theoretical weight: 53.05 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 30-502; Coverage: 55%)
Gene name: env
Sequence domains: Envelope glycoprotein GP120
Ab275MUR antibody Fab heavy chain Chains: D, H, J
Molecule details ›
Chains: D, H, J
Length: 122 amino acids
Theoretical weight: 13.42 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
Ab275MUR antibody Fab light chain Chains: E, K, L
Molecule details ›
Chains: E, K, L
Length: 218 amino acids
Theoretical weight: 23.94 KDa
Source organism: Mus musculus
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.4Å
Relevant EMDB volumes: EMD-20178
Expression system: Homo sapiens