6ok4

X-ray diffraction
2.4Å resolution

Crystal Structure of Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from Chlamydia trachomatis with bound NAD

Released:
Entry authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glyceraldehyde-3-phosphate dehydrogenase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 342 amino acids
Theoretical weight: 37.36 KDa
Source organism: Chlamydia trachomatis D/UW-3/CX
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0CE13 (Residues: 1-334; Coverage: 100%)
Gene names: CT_505, gap, gapA
Sequence domains:

Ligands and Environments


Cofactor: Ligand NAD 4 x NAD

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P212121
Unit cell:
a: 86.47Å b: 135.29Å c: 137.67Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.174 0.172 0.208
Expression system: Escherichia coli BL21(DE3)