› 6ojq

Electron Microscopy
3.67Å resolution

Monomeric kinesin-1 motor domain in no-nucleotide state bound to GMPCPP-stabilized microtubule

Released:
DOI: 10.2210/pdb6ojq/pdb
PDB entry 6ojq coloured by chain, front view.
PDB entry 6ojq coloured by chain, side view.
PDB entry 6ojq coloured by chain, top view.
Source organisms:
Entry authors: Cha HK, Debs G
Related structures: EMD-20092

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-152550 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Tubulin beta-2B chain Chain: B
Molecule details ›
Chain: B
Length: 426 amino acids
Theoretical weight: 47.83 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: Q6B856 (Residues: 1-426; Coverage: 96%)
Gene name: TUBB2B
Sequence domains:
Tubulin alpha-1B chain Chain: A
Molecule details ›
Chain: A
Length: 437 amino acids
Theoretical weight: 48.67 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P81947 (Residues: 1-437; Coverage: 97%)
Sequence domains:
Kinesin-1 heavy chain Chain: K
Molecule details ›
Chain: K
Length: 317 amino acids
Theoretical weight: 35.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P33176 (Residues: 8-324; Coverage: 33%)
Gene names: KIF5B, KNS, KNS1
Sequence domains: Kinesin motor domain

Ligands and Environments

3 bound ligands:
Ligand G2P 1 x G2P
Ligand MG 2 x MG
Ligand GTP 1 x GTP
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.67Å
Relevant EMDB volumes: EMD-20092
Expression system: Escherichia coli

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