› › Structure analysis

Muscarinic acetylcholine receptor 1-G11 protein complex

Electron Microscopy
3.3Å resolution
PDB entry 6oij coloured by chain, front view.
PDB entry 6oij coloured by chain, side view.
PDB entry 6oij coloured by chain, top view.
Source organisms:
Assembly composition:
hetero pentamer (preferred)
Entry contents: 5 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: hetero pentamer
Accessible surface area: 50048.32 Å2
Buried surface area: 11664.34 Å2
Dissociation area: 971.29 Å2
Dissociation energy (ΔGdiss): -1.28 kcal/mol
Dissociation entropy (TΔSdiss): 13.55 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-207446

Macromolecules

G protein subunit alpha i1; Guanine nucleotide-binding protein subunit alpha-11
Chain: A
Length: 353 amino acids
Theoretical weight: 41.27 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: A0A3B3ITX3 (Residues: 1-30; Coverage: 50%)
  • Canonical: P29992 (Residues: 37-359; Coverage: 90%)
    • nullnull
Gene names: GA11, GNA11, GNAI1
Pfam: G-protein alpha subunit
InterPro:
G protein subunit alpha i1 in PDB entry 6oij, assembly 1, front view.
G protein subunit alpha i1 in PDB entry 6oij, assembly 1, side view.
G protein subunit alpha i1 in PDB entry 6oij, assembly 1, top view.
Molecule details ›

Search similar proteins

Muscarinic acetylcholine receptor M1
Chain: R
Length: 363 amino acids
Theoretical weight: 41.24 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P11229 (Residues: 2-460; Coverage: 75%)
Gene name: CHRM1
Pfam: 7 transmembrane receptor (rhodopsin family)
InterPro:
Muscarinic acetylcholine receptor M1 in PDB entry 6oij, assembly 1, front view.
Muscarinic acetylcholine receptor M1 in PDB entry 6oij, assembly 1, side view.
Muscarinic acetylcholine receptor M1 in PDB entry 6oij, assembly 1, top view.
Molecule details ›

Search similar proteins

Antibody fragment
Chain: H
Length: 256 amino acids
Theoretical weight: 27.34 KDa
Source organism: Mus musculus
Expression system: Trichoplusia ni
InterPro:
CATH: Immunoglobulins
Antibody fragment in PDB entry 6oij, assembly 1, front view.
Antibody fragment in PDB entry 6oij, assembly 1, side view.
Antibody fragment in PDB entry 6oij, assembly 1, top view.
Molecule details ›

Search similar proteins

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Chain: B
Length: 345 amino acids
Theoretical weight: 37.73 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P62873 (Residues: 2-340; Coverage: 100%)
Gene name: GNB1
Pfam: WD domain, G-beta repeat
InterPro:
CATH: YVTN repeat-like/Quinoprotein amine dehydrogenase
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 in PDB entry 6oij, assembly 1, front view.
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 in PDB entry 6oij, assembly 1, side view.
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 in PDB entry 6oij, assembly 1, top view.
Molecule details ›

Search similar proteins

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
Chain: G
Length: 71 amino acids
Theoretical weight: 7.86 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P59768 (Residues: 1-71; Coverage: 100%)
Gene name: GNG2
Pfam: GGL domain
InterPro:
CATH: Transducin (heterotrimeric G protein), gamma chain
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 in PDB entry 6oij, assembly 1, front view.
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 in PDB entry 6oij, assembly 1, side view.
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 in PDB entry 6oij, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links