PDBe 6ogz

Electron Microscopy
3.6Å resolution

In situ structure of Rotavirus RNA-dependent RNA polymerase at transcript-elongated state

Released:

Function and Biology Details

Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero 13-mer (preferred)
Entry contents:
2 distinct polypeptide molecules
2 distinct RNA molecules
Macromolecules (4 distinct):
RNA-directed RNA polymerase Chain: A
Molecule details ›
Chain: A
Length: 1088 amino acids
Theoretical weight: 125.28 KDa
Source organism: Rotavirus A
UniProt:
  • Canonical: G0YZJ9 (Residues: 1-1088; Coverage: 100%)
Inner capsid protein VP2 Chains: E, F, G, H, I, J, K, L, M, N
Molecule details ›
Chains: E, F, G, H, I, J, K, L, M, N
Length: 887 amino acids
Theoretical weight: 103.43 KDa
Source organism: Rotavirus A
UniProt:
  • Canonical: G0YZK0 (Residues: 1-887; Coverage: 100%)
RNA (5'-R(P*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*A)-3') Chain: B
Molecule details ›
Chain: B
Length: 18 nucleotides
Theoretical weight: 5.67 KDa
RNA (5'-R(P*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*A)-3') Chain: C
Molecule details ›
Chain: C
Length: 17 nucleotides
Theoretical weight: 5.37 KDa

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.6Å
Relevant EMDB volumes: EMD-20060