› 6ocq

X-ray diffraction
2.79Å resolution

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171747 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Receptor-interacting serine/threonine-protein kinase 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 303 amino acids
Theoretical weight: 34.6 KDa
Source organism: Homo sapiens
Expression system: Spodoptera aff. frugiperda 2 RZ-2014
UniProt:
  • Canonical: Q13546 (Residues: 1-294; Coverage: 44%)
Gene names: RIP, RIP1, RIPK1
Sequence domains: Protein tyrosine and serine/threonine kinase
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand M5J 2 x M5J
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P212121
Unit cell:
a: 47.297Å b: 95.117Å c: 127.24Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.203 0.268
Expression system: Spodoptera aff. frugiperda 2 RZ-2014

Quick links

Citations

7 review citations

Cell death pathways: intricate connections and disease implications.
Kist et al. (2021)
6 more