› 6ocj

X-ray diffraction
2.5Å resolution

Crystal Structure of Equine Serum Albumin in Complex with Suprofen

Released:
DOI: 10.2210/pdb6ocj/pdb
PDB entry 6ocj coloured by chain, front view.
PDB entry 6ocj coloured by chain, side view.
PDB entry 6ocj coloured by chain, top view.
Source organism: Equus caballus
Primary publication:
Structural investigations of stereoselective profen binding by equine and leporine serum albumins.
Zielinski K, Sekula B, Bujacz A, Szymczak I
Chirality 32 334-344 (2020)
PMID: 31905261

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153012 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Albumin Chain: A
Molecule details ›
Chain: A
Length: 583 amino acids
Theoretical weight: 65.63 KDa
Source organism: Equus caballus
UniProt:
  • Canonical: P35747 (Residues: 25-607; Coverage: 99%)
Gene name: ALB
Sequence domains: Serum albumin family

Ligands and Environments

4 bound ligands:
Ligand M5A 1 x M5A
Ligand MLI 1 x MLI
Ligand SIN 1 x SIN
Ligand ACT 1 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P61
Unit cell:
a: 95.261Å b: 95.261Å c: 144.533Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.202 0.198 0.26

Quick links

Citations

2 review citations

Enantioselectivity in Drug Pharmacokinetics and Toxicity: Pharmacological Relevance and Analytical Methods.
Coelho et al. (2021)
1 more

2 mentions without citation

Albumin-Based Transport of Nonsteroidal Anti-Inflammatory Drugs in Mammalian Blood Plasma.
Czub et al. (2020)
1 more