6obt

X-ray diffraction
1.8Å resolution

Structural insights into dehydratase substrate selection for the borrelidin and fluvirucin polyketide synthases

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carrier domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 314 amino acids
Theoretical weight: 33.76 KDa
Source organism: Streptomyces parvulus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q70I00 (Residues: 2588-2859; Coverage: 8%)
Gene name: borA3
Sequence domains: Polyketide synthase dehydratase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: C2
Unit cell:
a: 108.21Å b: 63.35Å c: 40.67Å
α: 90° β: 100.44° γ: 90°
R-values:
R R work R free
0.203 0.203 0.232
Expression system: Escherichia coli