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Nitrogenase MoFeP mutant S188A from Azotobacter vinelandii in the dithionite reduced state after redox cycling

Source organism: Azotobacter vinelandii
Biochemical function: iron-sulfur cluster binding
Biological process: nitrogen fixation
Cellular component: molybdenum-iron nitrogenase complex

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EC 1.18.6.1: Nitrogenase

Reaction catalysed:
8 reduced ferredoxin + 8 H(+) + N(2) + 16 ATP + 16 H(2)O = 8 oxidized ferredoxin + H(2) + 2 NH(3) + 16 ADP + 16 phosphate
Systematic name:
Ferredoxin:dinitrogen oxidoreductase (ATP-hydrolyzing, molybdenum-dependent)
Alternative Name(s):
  • Reduced ferredoxin:dinitrogen oxidoreductase (ATP-hydrolyzing)

GO terms

Sequence families

Pfam Protein families (Pfam)
PF00148
Domain description: Nitrogenase component 1 type Oxidoreductase
Occurring in:
  1. Nitrogenase molybdenum-iron protein alpha chain
  2. Nitrogenase molybdenum-iron protein beta chain
The deposited structure of PDB entry 6o7q contains 2 copies of Pfam domain PF00148 (Nitrogenase component 1 type Oxidoreductase) in Nitrogenase molybdenum-iron protein alpha chain. Showing 1 copy in chain C.
The deposited structure of PDB entry 6o7q contains 2 copies of Pfam domain PF00148 (Nitrogenase component 1 type Oxidoreductase) in Nitrogenase molybdenum-iron protein beta chain. Showing 1 copy in chain B.

PF11844
Domain description: Domain of unknown function (DUF3364)
Occurring in:
  1. Nitrogenase molybdenum-iron protein beta chain
The deposited structure of PDB entry 6o7q contains 2 copies of Pfam domain PF11844 (Domain of unknown function (DUF3364)) in Nitrogenase molybdenum-iron protein beta chain. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR000318
Domain description: Nitrogenase component 1, conserved site
Occurring in:
  1. Nitrogenase molybdenum-iron protein alpha chain
  2. Nitrogenase molybdenum-iron protein beta chain
IPR000510
Domain description: Nitrogenase/oxidoreductase, component 1
Occurring in:
  1. Nitrogenase molybdenum-iron protein alpha chain
  2. Nitrogenase molybdenum-iron protein beta chain
IPR005972
Domain description: Nitrogenase molybdenum-iron protein alpha chain
Occurring in:
  1. Nitrogenase molybdenum-iron protein alpha chain
IPR010143
Domain description: Nitrogenase component 1, alpha chain
Occurring in:
  1. Nitrogenase molybdenum-iron protein alpha chain
IPR005976
Domain description: Nitrogenase molybdenum-iron protein beta chain
Occurring in:
  1. Nitrogenase molybdenum-iron protein beta chain
IPR024564
Domain description: Nitrogenase molybdenum-iron protein beta chain, N-terminal
Occurring in:
  1. Nitrogenase molybdenum-iron protein beta chain

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