Function and Biology Details
Reaction catalysed:
ATP + H(2)O + lipid A-core oligosaccharide(Side 1) = ADP + phosphate + lipid A-core oligosaccharide(Side 2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- ABC transporter-like, ATP-binding domain
- P-loop containing nucleoside triphosphate hydrolase
- ABC transporter type 1, transmembrane domain
- ABC transporter type 1, transmembrane domain superfamily
- ABC transporter-like, conserved site
- AAA+ ATPase domain
- Type 1 protein exporter
- ABC transporter, lipid A-core flippase, MsbA
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
ATP-dependent lipid A-core flippase (preferred)
PDBe Complex ID:
PDB-CPX-159094 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-dependent lipid A-core flippase
Molecule details ›
Chains: A, B
Length: 576 amino acids
Theoretical weight: 63.67 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 576 amino acids
Theoretical weight: 63.67 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Expression system: Escherichia coli
UniProt:
- Canonical:
P63359 (Residues: 7-582; Coverage: 99%)
Sequence domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SSRL BEAMLINE BL11-1
Spacegroup:
P21212
Expression system: Escherichia coli
