Function and Biology Details
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Stimulator of interferon genes protein
- Protein kinase domain
- Stimulator of interferon genes protein, C-terminal domain superfamily
- Stimulator of interferon genes protein homolog, C-terminal
- Stimulator of interferon genes protein, C-terminal
- TANK-binding kinase 1, coiled-coil domain 1
- TANK binding kinase 1, ubiquitin-like domain
- Protein kinase, ATP binding site
1 more domain
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-122782 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Serine/threonine-protein kinase TBK1
Molecule details ›
Chains: A, B
Length: 742 amino acids
Theoretical weight: 85.32 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 742 amino acids
Theoretical weight: 85.32 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q9UHD2 (Residues: 1-729; Coverage: 100%)
Sequence domains:
- Protein kinase domain
- TANK binding kinase 1 ubiquitin-like domain
- TANK-binding kinase 1 coiled-coil domain 1
Stimulator of interferon genes protein
Molecule details ›
Chains: C, D
Length: 392 amino acids
Theoretical weight: 44.21 KDa
Source organism: Gallus gallus
Expression system: Homo sapiens
UniProt:
Sequence domains: Transmembrane protein 173
Length: 392 amino acids
Theoretical weight: 44.21 KDa
Source organism: Gallus gallus
Expression system: Homo sapiens
UniProt:
- Canonical: E1C7U0 (Residues: 1-379; Coverage: 100%)
Sequence domains: Transmembrane protein 173
