› 6naz

X-ray diffraction
3.08Å resolution

Crystal structure of DIRAS 2/3 chimera in complex with GDP

Released:
DOI: 10.2210/pdb6naz/pdb
PDB entry 6naz coloured by chain, front view.
PDB entry 6naz coloured by chain, side view.
PDB entry 6naz coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Gilbert YH, Reger A, Sharma R, Bast J, Kim C

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131981 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GTP-binding protein Di-Ras2; GTP-binding protein Di-Ras3 Chain: A
Molecule details ›
Chain: A
Length: 199 amino acids
Theoretical weight: 22.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96HU8 (Residues: 1-61, 83-199; Coverage: 89%)
  • Canonical: O95661 (Residues: 92-112; Coverage: 9%)
Gene names: ARHI, DIRAS2, DIRAS3, NOEY2, RHOI
Sequence domains: Ras family

Ligands and Environments

3 bound ligands:
Ligand GDP 1 x GDP
Ligand GOL 3 x GOL
Ligand EDO 3 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P6522
Unit cell:
a: 92.03Å b: 92.03Å c: 86.52Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.27 0.267 0.332
Expression system: Escherichia coli

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