6n3h

X-ray diffraction
2.6Å resolution

Crystal structure of Kelch domain of the human NS1 binding protein

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-195397 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Influenza virus NS1A-binding protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 331 amino acids
Theoretical weight: 36.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: Q9Y6Y0 (Residues: 321-642; Coverage: 50%)
Gene names: ARA3, FLARA3, HSPC068, IVNS1ABP, KIAA0850, KLHL39, NS1, NS1BP
Sequence domains: Kelch motif

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 77.196Å b: 61.885Å c: 87.339Å
α: 90° β: 95.18° γ: 90°
R-values:
R R work R free
0.212 0.211 0.234
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'