› 6n2u

X-ray diffraction
1.25Å resolution

IL-8 Structure from Bacterial Expression Source

Released:
DOI: 10.2210/pdb6n2u/pdb
PDB entry 6n2u coloured by chain, front view.
PDB entry 6n2u coloured by chain, side view.
PDB entry 6n2u coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Park H, Jung JH, Luo JL

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145181 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interleukin-8 Chain: A
Molecule details ›
Chain: A
Length: 99 amino acids
Theoretical weight: 11.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P10145 (Residues: 1-99; Coverage: 100%)
Gene names: CXCL8, IL8
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P3121
Unit cell:
a: 39.701Å b: 39.701Å c: 89.971Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.19 0.187 0.223
Expression system: Escherichia coli

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