6mtu

X-ray diffraction
2.14Å resolution

Crystal structure of human Scribble PDZ1:pMCC complex

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-149988 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein scribble homolog Chains: A, B
Molecule details ›
Chains: A, B
Length: 118 amino acids
Theoretical weight: 12.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14160 (Residues: 700-816; Coverage: 7%)
Gene names: CRIB1, KIAA0147, LAP4, SCRB1, SCRIB, VARTUL
Sequence domains: PDZ domain
Colorectal mutant cancer protein Chains: C, D
Molecule details ›
Chains: C, D
Length: 8 amino acids
Theoretical weight: 979 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P23508 (Residues: 822-829; Coverage: 1%)
Gene name: MCC

Ligands and Environments

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: I41
Unit cell:
a: 53.6Å b: 53.6Å c: 214.454Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.197 0.255
Expression systems:
  • Escherichia coli
  • Not provided