› › Structure analysis

Monoextended DARPin M_R12 complex with EpoR

X-ray diffraction
3.163Å resolution
PDB entry 6mol coloured by chain, front view.
PDB entry 6mol coloured by chain, side view.
PDB entry 6mol coloured by chain, top view.
Source organisms:
Assembly composition:
hetero trimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Erythropoietin receptor
hide full assembly name
Multimeric state: hetero trimer
Accessible surface area: 38898.63 Å2
Buried surface area: 4013.7 Å2
Dissociation area: 1,884.39 Å2
Dissociation energy (ΔGdiss): -10.38 kcal/mol
Dissociation entropy (TΔSdiss): 27.07 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-148536

Macromolecules

Monoextended DARPin R12 (M_R12)
Chain: A
Length: 461 amino acids
Theoretical weight: 48.22 KDa
Source organism: synthetic construct
Expression system: Escherichia coli
InterPro:
Monoextended DARPin R12 (M_R12) in PDB entry 6mol, assembly 1, front view.
Monoextended DARPin R12 (M_R12) in PDB entry 6mol, assembly 1, side view.
Monoextended DARPin R12 (M_R12) in PDB entry 6mol, assembly 1, top view.
Molecule details ›

Search similar proteins

Erythropoietin receptor
Chains: B, C
Length: 229 amino acids
Theoretical weight: 25.13 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P19235 (Residues: 32-249; Coverage: 45%)
Gene name: EPOR
Pfam:
InterPro:
Erythropoietin receptor in PDB entry 6mol, assembly 1, front view.
Erythropoietin receptor in PDB entry 6mol, assembly 1, side view.
Erythropoietin receptor in PDB entry 6mol, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links