6mkb

X-ray diffraction
2.5Å resolution

Crystal structure of murine 4-1BB ligand

Released:
Source organism: Mus musculus
Entry authors: Bitra A, Zajonc DM, Doukov T

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (5 distinct):
Tumor necrosis factor ligand superfamily member 9 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 171 amino acids
Theoretical weight: 19.26 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P41274 (Residues: 139-309; Coverage: 55%)
Gene names: Cd137l, Cd157l, Ly63l, Tnfsf9
Sequence domains: TNF(Tumour Necrosis Factor) family
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P31
Unit cell:
a: 77.362Å b: 77.362Å c: 118.236Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.191 0.188 0.241
Expression system: Spodoptera frugiperda