› 6mjh

X-ray diffraction
2.06Å resolution

The S31N mutant of the influenza A M2 proton channel in two distinct conformational states

Released:
DOI: 10.2210/pdb6mjh/pdb
PDB 6mjh coloured by chain and viewed from the front.
PDB 6mjh coloured by chain and viewed from the side.
PDB 6mjh coloured by chain and viewed from the top.
Source organism: Influenza A virus (A/pigeon/Jiangsu/K23/2013(H9N2))
Entry authors: Thomaston JL, DeGrado WF

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Matrix protein 2 Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 27 amino acids
Theoretical weight: 2.78 KDa
Source organism: Influenza A virus (A/pigeon/Jiangsu/K23/2013(H9N2))
Expression system: Not provided
UniProt:
  • Canonical: A0A0R5TVW3 (Residues: 20-44; Coverage: 28%)
Gene name: M2

Ligands and Environments

2 bound ligands:
Ligand CA 4 x CA
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P21
Unit cell:
a: 36.29Å b: 36.15Å c: 76.45Å
α: 90° β: 103.6° γ: 90°
R-values:
R R work R free
0.22 0.217 0.248
Expression system: Not provided

Quick links

Citations

1 review citation

Put a cork in it: Plugging the M2 viral ion channel to sink influenza.
Jalily et al. (2020)
6 other articles