› 6m78

Solution NMR

Aromatic interactions drive the coupled folding and binding of the intrinsically disordered Sesbania mosaic virus VPg protein

Released:
DOI: 10.2210/pdb6m78/pdb
PDB entry 6m78 coloured by chain, ensemble of 4 models, front view.
PDB entry 6m78 coloured by chain, ensemble of 4 models, side view.
PDB entry 6m78 coloured by chain, ensemble of 4 models, top view.
Source organism: Sesbania mosaic virus
Primary publication:
Aromatic Interactions Drive the Coupled Folding and Binding of the Intrinsically Disordered Sesbania mosaic Virus VPg Protein.
Dixit K, Karanth NM, Nair S, Kumari K, Chakrabarti KS, Savithri HS, Sarma SP
Biochemistry 59 4663-4680 (2020)
PMID: 33269926

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190143 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Peptidase S39 domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 296 amino acids
Theoretical weight: 32.25 KDa
Source organism: Sesbania mosaic virus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9EB08 (Residues: 120-402; Coverage: 50%)
Sequence domains: Peptidase S39
Peptidase S39 domain-containing protein Chain: B
Molecule details ›
Chain: B
Length: 80 amino acids
Theoretical weight: 9.11 KDa
Source organism: Sesbania mosaic virus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9EB08 (Residues: 326-402; Coverage: 14%)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 29%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

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Citations

3 citation in other articles

Minimizing Pervasive Artifacts in 4D Covariance Maps for Protein Side Chain NMR Assignments.
Kancherla et al. (2021)
2 more