Function and Biology Details
Reactions catalysed:
Peptidylproline (omega=180) = peptidylproline (omega=0)
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154618 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Peptidyl-prolyl cis-trans isomerase FKBP1A
Molecule details ›
Chains: A, E
Length: 110 amino acids
Theoretical weight: 12.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: FKBP-type peptidyl-prolyl cis-trans isomerase
Length: 110 amino acids
Theoretical weight: 12.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P62942 (Residues: 1-108; Coverage: 100%)
Sequence domains: FKBP-type peptidyl-prolyl cis-trans isomerase
Serine/threonine-protein kinase mTOR
Molecule details ›
Chains: B, F
Length: 95 amino acids
Theoretical weight: 11.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: FKBP12-rapamycin binding domain
Length: 95 amino acids
Theoretical weight: 11.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P42345 (Residues: 2021-2113; Coverage: 4%)
Sequence domains: FKBP12-rapamycin binding domain
