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Cryo-EM structure of human secretory immunoglobulin A in complex with the N-terminal domain of SpsA

Source organisms:
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF07686
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. Secretory component
The deposited structure of PDB entry 6lxw contains 5 copies of Pfam domain PF07686 (Immunoglobulin V-set domain) in Secretory component. Showing 5 copies in chain F [auth P].

PF07654
Domain description: Immunoglobulin C1-set domain
Occurring in:
  1. Immunoglobulin heavy constant alpha 1; Interleukin-2
The deposited structure of PDB entry 6lxw contains 4 copies of Pfam domain PF07654 (Immunoglobulin C1-set domain) in Immunoglobulin heavy constant alpha 1. Showing 1 copy in chain D.

PF00047
Domain description: Immunoglobulin domain
Occurring in:
  1. Immunoglobulin heavy constant alpha 1; Interleukin-2

PF05062
Domain description: RICH domain
Occurring in:
  1. SigA binding protein
The deposited structure of PDB entry 6lxw contains 1 copy of Pfam domain PF05062 (RICH domain) in SigA binding protein. Showing 1 copy in chain G [auth S] (this domain is out of the observed residue ranges!).

PF15097
Domain description: Immunoglobulin J chain
Occurring in:
  1. Immunoglobulin J chain
The deposited structure of PDB entry 6lxw contains 1 copy of Pfam domain PF15097 (Immunoglobulin J chain) in Immunoglobulin J chain. Showing 1 copy in chain E [auth J].

InterPro InterPro annotations
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. Immunoglobulin heavy constant alpha 1; Interleukin-2
  2. Secretory component
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. Immunoglobulin heavy constant alpha 1; Interleukin-2
  2. Secretory component
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. Immunoglobulin heavy constant alpha 1; Interleukin-2
  2. Secretory component
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. Secretory component
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. Immunoglobulin heavy constant alpha 1; Interleukin-2
IPR003599
Domain description: Immunoglobulin subtype
Occurring in:
  1. Secretory component
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. Immunoglobulin heavy constant alpha 1; Interleukin-2
IPR013151
Domain description: Immunoglobulin
Occurring in:
  1. Immunoglobulin heavy constant alpha 1; Interleukin-2
IPR024110
Domain description: Immunoglobulin J chain
Occurring in:
  1. Immunoglobulin J chain
IPR007756
Domain description: RICH domain
Occurring in:
  1. SigA binding protein
IPR038183
Domain description: RICH domain superfamily
Occurring in:
  1. SigA binding protein

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