Function and Biology Details
Reactions catalysed:
[RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate.]
[Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. Inother picornavirus reactions Glu may be substituted for Gln, and Ser orThr for Gly.]
[Selective cleavage of Tyr-|-Gly bond in the picornavirus polyprotein.]
[a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate+ phosphate + H(+).]
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Genome polyprotein and RNA (preferred)
PDBe Complex ID:
PDB-CPX-123004 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct RNA molecules
2 distinct RNA molecules
Macromolecules (3 distinct):
Genome polyprotein
Molecule details ›
Chain: A
Length: 468 amino acids
Theoretical weight: 53.41 KDa
Source organism: Enterovirus A71
Expression system: Escherichia coli BL21(DE3)
UniProt:
Length: 468 amino acids
Theoretical weight: 53.41 KDa
Source organism: Enterovirus A71
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
E5RPG3 (Residues: 1732-2193; Coverage: 21%)
