6lgl

Electron Microscopy
4.4Å resolution

The atomic structure of varicella-zoster virus A-capsid

Released:
Source organism: Human alphaherpesvirus 3
Entry authors: Zheng Q, Li S
Related structures: EMD-0880

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assemblies composition:
Non-polymer only 2760-mer (preferred)
Non-polymer only 46-mer
Non-polymer only 230-mer
Non-polymer only 276-mer
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Major capsid protein Chains: A, B, C, E, F, G, M, N, O, P, Q, R, S, T, U, z
Molecule details ›
Chains: A, B, C, E, F, G, M, N, O, P, Q, R, S, T, U, z
Length: 1396 amino acids
Theoretical weight: 155.15 KDa
Source organism: Human alphaherpesvirus 3
UniProt:
  • Canonical: Q6QCL5 (Residues: 1-1396; Coverage: 100%)
Gene names: HHV3_E_SVETAgp42, HHV3_gp42, HHV3gp42, MCP, ORF 40, ORF40
Sequence domains: Herpes virus major capsid protein
Small capsomere-interacting protein Chains: D, H, I, J, K, L, V, W, X, Y, Z, a, b, c, d
Molecule details ›
Chains: D, H, I, J, K, L, V, W, X, Y, Z, a, b, c, d
Length: 235 amino acids
Theoretical weight: 24.44 KDa
Source organism: Human alphaherpesvirus 3
UniProt:
  • Canonical: Q6QCN2 (Residues: 1-235; Coverage: 100%)
Gene names: HHV3M2gp25, HHV3_E_SVETAgp25, HHV3_gp25, HHV3gp25, ORF 23, ORF23, SCP
Sequence domains: Herpesvirus UL35 family
Triplex capsid protein 1 Chains: e, f, g, h, i
Molecule details ›
Chains: e, f, g, h, i
Length: 483 amino acids
Theoretical weight: 54.03 KDa
Source organism: Human alphaherpesvirus 3
UniProt:
  • Canonical: Q6QCN5 (Residues: 1-483; Coverage: 100%)
Gene names: HHV3M2gp22, HHV3_E_SVETAgp22, HHV3_gp22, HHV3gp22, ORF 20, ORF20, TRX1
Sequence domains: Herpesvirus capsid shell protein VP19C
Triplex capsid protein 2 Chains: j, k, l, m, n, o, p, q, r, s
Molecule details ›
Chains: j, k, l, m, n, o, p, q, r, s
Length: 316 amino acids
Theoretical weight: 34.42 KDa
Source organism: Human alphaherpesvirus 3
UniProt:
  • Canonical: Q6QCL4 (Residues: 1-316; Coverage: 100%)
Gene names: HHV3M2gp43, HHV3_E_SVETAgp43, HHV3_gp43, HHV3gp43, ORF 41, ORF41, TRX2
Sequence domains: Herpesvirus VP23 like capsid protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.4Å
Relevant EMDB volumes: EMD-0880