› 6l9f

X-ray diffraction
2.56Å resolution

Crystal structure of TEAD4 in complex with a novel FAM181A peptide

Released:
DOI: 10.2210/pdb6l9f/pdb
PDB entry 6l9f coloured by chain, front view.
PDB entry 6l9f coloured by chain, side view.
PDB entry 6l9f coloured by chain, top view.
Source organisms:
Entry authors: Chen M, Zhou Z

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178931 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transcriptional enhancer factor TEF-3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 222 amino acids
Theoretical weight: 26.17 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q62296 (Residues: 209-427; Coverage: 51%)
Gene names: Tcf13r1, Tead4, Tef3, Tefr1
Sequence domains: YAP binding domain
Protein FAM181A Chains: C, D
Molecule details ›
Chains: C, D
Length: 20 amino acids
Theoretical weight: 2.41 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q8N9Y4 (Residues: 187-206; Coverage: 6%)
Gene names: C14orf152, FAM181A, HSD-31, HSD31

Ligands and Environments

1 bound ligand:
Ligand ACT 5 x ACT
1 modified residue:
Ligand P1L 2 x P1L

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: P6422
Unit cell:
a: 110.009Å b: 110.009Å c: 182.711Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.196 0.19 0.253
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

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