› 6l30

X-ray diffraction
2.8Å resolution

Crystal structure of the epithelial cell transforming 2 (ECT2)

Released:
DOI: 10.2210/pdb6l30/pdb
PDB entry 6l30 coloured by chain, front view.
PDB entry 6l30 coloured by chain, side view.
PDB entry 6l30 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure and regulation of human epithelial cell transforming 2 protein.
Chen M, Pan H, Sun L, Shi P, Zhang Y, Li L, Huang Y, Chen J, Jiang P, Fang X, Wu C, Chen Z
Proc Natl Acad Sci U S A 117 1027-1035 (2020)
PMID: 31888991

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190684 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein ECT2 Chain: A
Molecule details ›
Chain: A
Length: 707 amino acids
Theoretical weight: 80.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H8V3 (Residues: 173-865; Coverage: 76%)
Gene name: ECT2
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: I222
Unit cell:
a: 106.959Å b: 130.579Å c: 131.773Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.238 0.237 0.269
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Advances in Hydrogen/Deuterium Exchange Mass Spectrometry and the Pursuit of Challenging Biological Systems.
James et al. (2022)
6 more

2 mentions without citation

Structure and regulation of human epithelial cell transforming 2 protein.
Chen et al. (2020)
1 more