X-ray diffraction
1.58Å resolution

b-glucuronidase from Ruminococcus gnavus in complex with D-glucaro 1,5-lactone


Function and Biology Details

Reaction catalysed:
Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Beta-galactosidase Chains: A, B
Molecule details ›
Chains: A, B
Length: 603 amino acids
Theoretical weight: 70.04 KDa
Source organism: [Ruminococcus] gnavus
Expression system: Escherichia coli
  • Canonical: Q6W7J7 (Residues: 1-603; Coverage: 100%)
Gene name: uidA
Sequence domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL13C1
Spacegroup: C2
Unit cell:
a: 162.56Å b: 103.345Å c: 112.281Å
α: 90° β: 130.99° γ: 90°
R R work R free
0.162 0.162 0.174
Expression system: Escherichia coli