Function and Biology Details
Reaction catalysed:
S-adenosyl-L-methionine + cytidine(32)/guanosine(34) in tRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytidine(32)/2'-O-methylguanosine(34) in tRNA
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- WD40 repeat
- WD40/YVTN repeat-like-containing domain superfamily
- WD40-repeat-containing domain superfamily
- S-adenosyl-L-methionine-dependent methyltransferase superfamily
- WD40 repeat, conserved site
- Ribosomal RNA methyltransferase, FtsJ domain
- Ribosomal RNA large subunit methyltransferase E
- tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase TRM7
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153586 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
tRNA (34-2'-O)-methyltransferase regulator RTT10
Molecule details ›
Chains: A, C
Length: 1028 amino acids
Theoretical weight: 116.39 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
Sequence domains: WD domain, G-beta repeat
Length: 1028 amino acids
Theoretical weight: 116.39 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
- Canonical:
Q08924 (Residues: 1-1013; Coverage: 100%)
Sequence domains: WD domain, G-beta repeat
tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase
Molecule details ›
Chains: B, D
Length: 325 amino acids
Theoretical weight: 36.55 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
Sequence domains: FtsJ-like methyltransferase
Length: 325 amino acids
Theoretical weight: 36.55 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
- Canonical: P38238 (Residues: 1-310; Coverage: 100%)
Sequence domains: FtsJ-like methyltransferase
