› 6jmv

X-ray diffraction
1.83Å resolution

Crystal structure of the GluK3 ligand binding domain complex with SYM and zinc

Released:
DOI: 10.2210/pdb6jmv/pdb
PDB entry 6jmv coloured by chain, front view.
PDB entry 6jmv coloured by chain, side view.
PDB entry 6jmv coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Structural and Functional Insights into GluK3-kainate Receptor Desensitization and Recovery.
Kumari J, Vinnakota R, Kumar J
Sci Rep 9 10254 (2019)
PMID: 31311973

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154591 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamate receptor ionotropic, kainate 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 257 amino acids
Theoretical weight: 29.05 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P42264 (Residues: 433-546, 669-807; Coverage: 29%)
Gene names: Glur7, Grik3
Sequence domains:

Ligands and Environments

6 bound ligands:
Ligand SYM 2 x SYM
Ligand CL 4 x CL
Ligand ZN 4 x ZN
Ligand GOL 5 x GOL
Ligand ACT 6 x ACT
Ligand NA 2 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Unit cell:
a: 56.46Å b: 88.03Å c: 130.47Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.203 0.242
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels.
Hansen et al. (2021)
3 more

1 mention without citation

Structural and Functional Insights into GluK3-kainate Receptor Desensitization and Recovery.
Kumari et al. (2019)