X-ray diffraction
2.5Å resolution

Crystal structure of methylated PRRSV nsp10 (helicase)


Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Non-structural protein 8 Chain: A
Molecule details ›
Chain: A
Length: 441 amino acids
Theoretical weight: 49.03 KDa
Source organism: Porcine reproductive and respiratory syndrome virus
Expression system: Escherichia coli
  • Canonical: J9XNG9 (Residues: 644-1084; Coverage: 30%)
Sequence domains: Viral (Superfamily 1) RNA helicase

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: P43212
Unit cell:
a: 93.158Å b: 93.158Å c: 148.108Å
α: 90° β: 90° γ: 90°
R R work R free
0.237 0.235 0.272
Expression system: Escherichia coli