6jci

X-ray diffraction
1.49Å resolution

Crystal structure of Prolyl Endopeptidase from Haliotis discus hannai with SUAM-14746

Released:
Source organism: Haliotis discus hannai
Entry authors: Li W, Cao M

Function and Biology Details

Reaction catalysed:
Hydrolysis of --Pro-|- and to a lesser extent --Ala-|- in oligopeptides.
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Prolyl endopeptidase Chain: A
Molecule details ›
Chain: A
Length: 758 amino acids
Theoretical weight: 85.88 KDa
Source organism: Haliotis discus hannai
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A1X9T5X9 (Residues: 1-706; Coverage: 100%)
Gene name: PREP
Sequence domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: P212121
Unit cell:
a: 53.57Å b: 104.84Å c: 137.98Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.178 0.194
Expression system: Escherichia coli BL21(DE3)