6jb3

Electron Microscopy
3Å resolution

Structure of SUR1 subunit bound with repaglinide

Released:
Source organism: Mesocricetus auratus
Primary publication:
The Structural Basis for the Binding of Repaglinide to the Pancreatic KATP Channel.
Cell Rep 27 1848-1857.e4 (2019)
PMID: 31067468
Related structures: EMD-9788

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-103766 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-binding cassette sub-family C member 8 isoform X2 Chain: B
Molecule details ›
Chain: B
Length: 1582 amino acids
Theoretical weight: 177.3 KDa
Source organism: Mesocricetus auratus
Expression system: Homo sapiens
UniProt:
  • Canonical: A0A1U7R319 (Residues: 1-1582; Coverage: 100%)
Gene name: Abcc8
Sequence domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.001Å
Relevant EMDB volumes: EMD-9788
Expression system: Homo sapiens